By Donald Y.M. Leung, Malcolm W. Greaves
This state-of-the-science reference presents necessary info at the pathophysiology and financial and social outcomes of allergic epidermis reactions, in addition to new remedies according to rising strategies of dermis ailment pathobiology-addressing the epidemiology, mechanisms, occupational results, environmental triggers, and quality-of-life issues. specializes in atopic dermatitis, urticaria, and allergic touch dermatitis, between different more and more universal epidermis problems. Written by way of greater than 35 major researchers, Allergic pores and skin affliction ·reviews simple ideas of the explanations of allergic epidermis responses ·analyzes the position of key phone kinds, effector molecules, cytokines, mediators, chemokines, mobilephone adhesion molecules, and immunogenetic mechanisms ·showcases the dynamics of adhesion molecules and the pathophysiology of pruritus ·examines scientific positive factors of epidermis bronchial asthma, fairly concerning immune mechanisms that make certain pathogenic path and end result ·investigates behaviors of keratinocytes, dendritic cells and macrophages, fibroblasts, lymphocytes, granulocytes, and endothelial cells ·explores phototherapy, photochemotherapy, immunomodulatory remedy, and conventional antiinflammatory treatment for recalcitrant pores and skin illnesses ·discusses anaphylaxis and different allergies to insect bites ·surveys demographism, vibratory angioedema, and different varieties of urticaria ·identifies allergic and infectious triggers of pores and skin disorder ·and extra! Containing over 1800 bibliographic citations, Allergic dermis sickness is a must-read source for dermatologists, allergists, immunologists, pharmaceutical and beauty chemists, internists, pediatricians, and graduate and scientific university scholars in those disciplines.
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Extra info for Allergic skin disease: a multidisciplinary approach
Prevalence of allergic rhinitis and atopic dermatitis among children in four regions of Finland. Allergy 1998; 53:682–689. 23. Hattevig G, Kjellman B, Björkstén B, Johansson SGO. The prevalence of allergy and IgE antibodies to inhalant allergens in Swedish school children. Acta Pediatr Scand 1987; 76: 349–355. 24. Croner S, Kjellman N-IM. Development of atopic disease in relation to family history and cord blood IgE levels. Pediatr Allergy Immunol 1990; 1:14–20. 25. Åberg N, Hesselmar B, Åberg B, Eriksson B.
CONCLUSIONS The available data confirm that allergic skin disease is a growing socioeconomic problem that has a major impact on occupational performance and the quality of life of millions of people. A rather conservative estimate of 25–40% of humans will suffer from one or Page 13 more allergic skin diseases during their lifetime. S. costs reached $5 billion annually. If the rising frequency of allergic skin diseases continues, it seems that in the future every human being will suffer from a more or less distressing allergic skin problem during his or her lifetime.
Acta Derm Venereol (Stockh) 1982; 62:237–240. 107. Ros A-M, Wennersten G. Current aspects of polymorphous light eruption in Sweden. Photodermatology 1986; 3:298–302. 108. Selvaag E. Clinical drug photosensitivity. A retrospective analysis of reports to the Norwe- Page 18 gian Adverse Drug Reactions Committee from years 1970–1994. Photodermatol Photoimmunol Photomed 1997; 13:21–23. 109. Nutter AF. Contact urticaria to rubber. Br J Dermatol 1979; 101:597–598. 110. Arellano R, Bradley J, Sussman G.
Allergic skin disease: a multidisciplinary approach by Donald Y.M. Leung, Malcolm W. Greaves